https://www.physio-pedia.com/Advanced_Myofascial_Release_Technique_for_Chronic_Pain_Management
Myofascial release (MFR) is a manual therapy technique aimed at alleviating pain and restoring movement by releasing tension in the fascia. Advanced myofascial release techniques are designed for practitioners to address chronic pain conditions more effectively. Chronic pain is often linked to fascial restrictions that can lead to musculoskeletal dysfunction. Myofascial release focuses on the fascia, the connective tissue that surrounds muscles, organs, and nerves, facilitating a holistic approach to pain management. Research indicates that myofascial release can lead to significant improvements in pain levels and functional mobility. A study published in the Journal of Bodywork and Movement Therapies[1] found that patients receiving MFR reported reductions in pain and an improved quality of life. Advanced Myofascial Release (AMFR) is a manual therapy technique that targets the fascia—the connective tissue that envelops muscles, organs, and nerves. This approach aims to alleviate chronic pain and enhance mobility by addressing restrictions within the fascia.
Furthermore, a study by Bove and Chapelle (2016) demonstrated the effectiveness of massage therapy in reducing fibrosis and promoting tissue repair, highlighting the importance of massage in managing scar tissue and enhancing the quality of tissue repair through collagen remodeling.
Conclusion
Massage therapy plays a significant role in collagen remodeling, offering benefits in tissue repair, healing, and functionality. Through mechanisms such as fibroblast stimulation, enhanced circulation, application of mechanical stress, and reduction of inflammation, massage therapy can support the body’s natural healing processes. This contribution to collagen remodeling underscores the therapeutic value of massage in various clinical and aesthetic applications, from sports injuries to skin health and anti-aging treatments.
The influence of massage on apoptotic signaling may be one explanation for its physiologic benefits. Apoptotic signaling of neutrophils has been shown to influence a phenotype change in the macrophage population.56 The M1 macrophages, which are phagocytic, seek and engulf apoptotic cells and lysed fragments. If an M1 macrophage engulfs an apoptotic cell rather than its lysed parts, it can influence a phenotypic change in which the M1 macrophage transitions to an M2 macrophage, secreting anti-inflammatory products.15,56 Macrophages that engulf apoptotic neutrophils prevent the release of neutrophil cytotoxic chemicals, ceasing respiratory burst and increasing the secretion of transforming growth factor β and interleukin 4.15,56 The release of transforming growth factor β and interleukin 4 results in decreased release of proinflammatory cytokines (eg, tumor necrosis factor α and interleukin 6) and promotes a transition to the Th2 cytokine pathway (Figure).15,56 The anti-inflammatory nature of the Th2 pathway promotes the repair and regenerative process.20,45,46
Using massage to influence phenotype change, prompting the transition into the repair and regeneration phase, may play an important role in the physiologic benefits of massage. Preventing the exacerbation of a toxic environment through the attenuation of neutrophil recruitment, respiratory burst, or the phagocytosis of apoptotic neutrophils also would greatly decrease endogenous chemical availability and the potential of nerve sensitization. In doing so, massage may be able to prevent transient and more detrimental plastic changes in afferent nerve density in the periphery and the spinal cord. Attenuating the inflammatory and subsequent nervous response may allow clinicians to treat, manage, and prevent acute and chronic pain syndromes, as well as inflammatory-related diseases, with massage and without pharmaceutical intervention.
Waters-Banker, C., Dupont-Versteegden, E. E., Kitzman, P. H., & Butterfield, T. A. (2014). Investigating the mechanisms of massage efficacy: the role of mechanical immunomodulation. Journal of athletic training, 49(2), 266–273. https://doi.org/10.4085/1062-6050-49.2.25
The Combination of Electroacupuncture and Massage Therapy Alleviates Myofibroblast Transdifferentiation and Extracellular Matrix Production in Blunt Trauma-Induced Skeletal Muscle Fibrosis
July 2021Evidence-based Complementary and Alternative Medicine 2021(17):1-10
DOI:10.1155/2021/5543468
Na Zhao, N., Liu, B., Si-Wen Liu, S., et al.
Zhao, N., Liu, B., Liu, S. W., Zhang, W., Li, H. N., Pang, G., Luo, X. F., & Wang, J. G. (2021). The Combination of Electroacupuncture and Massage Therapy Alleviates Myofibroblast Transdifferentiation and Extracellular Matrix Production in Blunt Trauma-Induced Skeletal Muscle Fibrosis. Evidence-based complementary and alternative medicine : eCAM, 2021, 5543468. https://doi.org/10.1155/2021/5543468
Warpenburg M. J. (2014). Deep Friction Massage in Treatment of Radiation-induced Fibrosis: Rehabilitative Care for Breast Cancer Survivors. Integrative medicine (Encinitas, Calif.), 13(5), 32–36.
Waters-Banker, C., Dupont-Versteegden, E. E., Kitzman, P. H., & Butterfield, T. A. (2014). Investigating the mechanisms of massage efficacy: the role of mechanical immunomodulation. Journal of athletic training, 49(2), 266–273. https://doi.org/10.4085/1062-6050-49.2.25
Van Pelt, D. W., Lawrence, M. M., Miller, B. F., Butterfield, T. A., & Dupont-Versteegden, E. E. (2021). Massage as a Mechanotherapy for Skeletal Muscle. Exercise and sport sciences reviews, 49(2), 107–114. https://doi.org/10.1249/JES.0000000000000244
https://www.ncbi.nlm.nih.gov/books/NBK513227
https://www.ncbi.nlm.nih.gov/books/NBK559051/
Osteopathic Manipulative Treatment: Lymphatic Procedures
Massage doesn’t just make muscles feel better, it makes them heal faster and stronger
Massage doesn’t just make muscles feel better, it makes them heal faster and stronger
Arthrofibrosis
https://www.abmp.com/massage-and-bodywork-magazine/arthrofibrosis-problems

